Trilostane Treating Brest Cancer Steroids Powder Chemical Raw Steroids Trilostane
|FOB Unit Price:||US $1.5 US $0.8|
|Purchase Qty. (g)||FOB Unit Price|
|Payment Terms:||T/T, Western Union, Money Gram|
- Model NO.: DMK581
- Customized: Non-Customized
- Suitable for: Elderly, Adult
- Purity: >99%
- MW: 329.43
- Trademark: DMK
- Specification: API
- HS Code: 29061310
- Powder: Yes
- Certification: GMP, ISO 9001, USP, BP
- State: Solid
- Mf: C20h27no3
- CAS: 13647-35-3
- Transport Package: Foil Bag
- Origin: China
Product name: Trilostane,Vetoryl,Desopan,Modrastane,Modrenal,Modrefen
CAS No.: 13647-35-3
Molecular formula: C20H27NO3
Molecular weight: 329.43
Appearance: White crystalline powder
Grade : Pharmaceutical Grade
Storage: Shading, confined preservation
Usage : Trilostane can inhibit cortical hormone in the process of synthesis of 3 beta dehydrogenase, make the cortisol, aldosterone synthesis decreased, clinically used in the treatment of Cushing syndrome (hypercortisolism) and primary aldosteronism. This product also had significantly effect to decreased serum testosterone level.
Trilostane is an inhibitor of isoforms 3β-HSD and 3β-HSD2 of the enzyme 3β-hydroxysteroid dehydrogenase,
which plays a role in adrenal steroid biosynthesis. Investigators believe
that Arg195 in 3β-HSD versus Pro195 in 3β-HSD2 attributes to the competitive inhibition of
3β-HSD, but not
3βHSD2 by Trilostane. Research shows that trilostane is effective in suppressing the intracellular
production oin LNCaPFGC prostate cancer cells and inhibiting cortisol biosynthesis in the human
adrenal gland. This product serves as a useful tool in steroid biosynthesis research.
Trilostane is used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushing's syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland.
Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroids by 3-beta-hydroxysteroid dehydrogenase/delta 5, 4 ketosteroid isomerase, thus blocking synthesis of adrenal steroids.
Side effect: Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin rash, and/or vomiting.
Payment Terms:T/T , Moneygram , Western Union.
1. Sent out in 24hours once payment comfirm.
2. Professional agent make sure our ship fastly and safety
3.Offer your tracking number to you once we get it ,in order to facilitate you track the express
1.How about parcel delivery success rate ?
Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%. As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.
2.What is The Minimum And Maximum Amount Of Steroid Powder I Can Order At One Time?
Normally, our min.order quantity is 10g,please feel free to contact us about the specific order.
We suggest the net weight of each package should be less than 3.5kg. But if your order quantity is more than 3.5 kg, we will split the goods into several packages and then send you separately.
3.Do You Ship Over The Weekend?
We use EMS,TNT,FEDEX,DHL four kinds of couriers. EMS don't collected parcels over the weekend. The packages can be shipped out normally before 12:00 a.m in Beijing time if you choose to ship by TNT or FedEx.