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Wuhan Demeikai Biotechnology Co., Ltd.

Mmad, Mmad Powder, Mmad Price manufacturer / supplier in China, offering Best Quality&Good Price Mmad Inhibitor of Tubulin CAS: 203849-91-6, Methenolone Enanthate Lean Muscle Steroids Injectable Anabolic Liquid Me 100, USP Standard Diethylstilbestrol Chemicals Steroids CAS56-53-1 China Suppliers and so on.

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Supplier Homepage Product ADCs Best Quality&Good Price Mmad Inhibitor of Tubulin CAS: 203849-91-6

Best Quality&Good Price Mmad Inhibitor of Tubulin CAS: 203849-91-6

FOB Price: US $1.5 / g
Min. Order: 10 g
Min. Order FOB Price
10 g US $1.5/ g
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Port: Shanghai, China
Production Capacity: 100kg/Y
Payment Terms: T/T, Western Union, Money Gram

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Basic Info
  • Powder: Yes
  • Certification: GMP, ISO 9001, USP
  • State: Solid
  • Mf: C41h66n6o6s
  • CAS: 203849-91-6
  • Transport Package: Aluminum Foil Bag/Carton
  • Origin: China
  • Customized: Non-Customized
  • Suitable for: Adult
  • Purity: >99%
  • MW: N/a
  • Trademark: DMK
  • Specification: API
  • HS Code: 29061310
Product Description

Product name:MonoMethyl Dolastatin 10
Synonyms:DeMethyldolastatin 10;MMAD;MonoMethyl Dolastatin 10;MonoMethylauristatin D;(S)-N-((3R,4S,5S)-3-methoxy-1-((S)-2-((1R,2R)-1-methoxy-2-methyl-3-oxo-3-(((S)-2-phenyl-1-(thiazol-2-yl)ethyl)amino)propyl)pyrrolidin-1-yl)-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide
CAS:203849-91-6
MF:C41H66N6O6S
General tips:For obtaining a higher solubility , please warm the tube at 37 ºC and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20ºC for several months.

MMAD Application:
MMAD is a highly potent inhibitor of tubulin . MMAD is one of the auristatins, which are used as the drugs of antibody drug conjugates (ADCs). In ADCs, the therapeutic compounds and the high selectivity of antibodies are combined by the linkers. By taking advantage of antigen-selectivity of MAbs, it can deliver these cytotoxic drugs to antigen-expressing tumor cells, thus increasing both the efficacy and safety of therapy. As a payload of ADCs, MMAD is used to target the tubulin of the tumor cells. It can interfere with tubulin polymerization and induce rapid cell death at low picomolar concentrations [1]. Additionally, MMAD is reported to be used in the production of site-specific antibody drug conjugates (NDCs). In the NDCs, MMAD is combined with anti-5T4 antibody or anti-Her2 antibody. It is shown that the NDCs demonstrate better efficacy and pharmacokinetics .


Real figure of MMAD  
Best Quality&Good Price Mmad Inhibitor of Tubulin CAS: 203849-91-6
MMAD packing :
Best Quality&Good Price Mmad Inhibitor of Tubulin CAS: 203849-91-6



 
Wuhan Deme chem Biotechnology Co., Ltd is a new and high-tech enterprise. 
The main business is research and development, production, sales for Steroid, Active ingredient and Pharmaceutical .
   
MMAD manufacturer production pictures:
Best Quality&Good Price Mmad Inhibitor of Tubulin CAS: 203849-91-6



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HydrocortisoneEp750-23-7
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Triamcinol0ne BaseBP/USP/EP124-94-7
HalcinonideCp20053093-35-4
16α-Hydroxy-Prednisoloneenterprise standard13951-70-7


Reason to choose us 

.Guarantee the quality of products ,our Pharmaceutical Intermediate purity≥99% .

.Variety diversification & Adequate stock make sure we could meet your require

.Professional service and rich experience ,we also could give you some advise about 
please feel free to contact us if you have any question.

Payment Term:T/T  , Moneygram , Western Union.

Delivery

1. Sent out in 24hours once payment comfirm.

2. Professional agent make sure our ship fastly and safety

3.Offer your tracking number to you once we get it ,in order to facilitate you track the express

 
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